We live in a time when words like local, handcrafted and organic all add perceived value to products.  We also pay large amounts of money for vintage wines that are produced far away by strangers.  This apparent conflict creates an opportunity for an entrepreneur to start a bar that sells  high end artisan mixed drinks.

Go after the niche that expensive wines now own.  All drinks would be locally crafted with fresh, organic ingredients.  The prices would be high enough to compete with high-end sushi.  Things like fresh basil martinis and organic mint juleps

This idea would combine the slow food movement, the local crafts movement and the creative arts in a package with the desire to drink large amounts alcohol in a socially acceptable manner.